Selected Publications
Full publication list on Pubmed
Liu, H., and Gregersen, L.H. (2025). Kinetic measurement of gene-specific RNA polymerase II transcription elongation rates. Genome Res. 10.1101/gr.280852.125.
Pappas, G., Munk, S.H.N., Watanabe, K., Thomas, Q., Gal, Z., Gram, H.H., Lee, M., Gomez-Cabello, D., Kanellis, D.C., Olivares-Chauvet, P., et al. (2023). MDC1 maintains active elongation complexes of RNA polymerase II. Cell Rep 42, 111979. 10.1016/j.celrep.2022.111979.
Gregersen, L.H., Mitter, R., and Svejstrup, J.Q. (2022). Elongation factor-specific capture of RNA polymerase II complexes. Cell Rep Methods 2, 100368. 10.1016/j.crmeth.2022.100368.
Gregersen, L.H., Mitter, R., and Svejstrup, J.Q. (2020). Using TT(chem)-seq for profiling nascent transcription and measuring transcript elongation. Nat Protoc 15, 604-627. 10.1038/s41596-019-0262-3.
Gregersen, L.H., Mitter, R., Ugalde, A.P., Nojima, T., Proudfoot, N.J., Agami, R., Stewart, A., and Svejstrup, J.Q. (2019). SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell 177, 1797-1813 e1718. 10.1016/j.cell.2019.04.038.
Gregersen, L.H., and Svejstrup, J.Q. (2018). The Cellular Response to Transcription-Blocking DNA Damage. Trends Biochem Sci 43, 327-341. 10.1016/j.tibs.2018.02.010.
Schueler, M., Munschauer, M., Gregersen, L.H., Finzel, A., Loewer, A., Chen, W., Landthaler, M., and Dieterich, C. (2014). Differential protein occupancy profiling of the mRNA transcriptome. Genome Biol 15, R15. 10.1186/gb-2014-15-1-r15.
Gregersen, L.H., Schueler, M., Munschauer, M., Mastrobuoni, G., Chen, W., Kempa, S., Dieterich, C., and Landthaler, M. (2014). MOV10 Is a 5′ to 3′ RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3′ UTRs. Mol Cell 54, 573-585. 10.1016/j.molcel.2014.03.017.
Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S.D., Gregersen, L.H., Munschauer, M., et al. (2013). Circular RNAs are a large class of animal RNAs with regulatory potency. Nature 495, 333-338. 10.1038/nature11928.